Untersuchen Sie diesen Bericht über haass
Untersuchen Sie diesen Bericht über haass
Blog Article
81377 München christian.haass(at)dzne.de +49 89 4400-46549 Areas of investigation/research focus Prof. Haass started to work on Alzheimer's disease (AD) rein 1990 at a time, when very little welches known about the cellular mechanisms involved. Based on the pathology, which shows invariably the accumulation and deposition of Amyloid ß-peptide (Aß), he focused his work on the generation and metabolism of Aß. Christian Haass hypothesized against the widely accepted general opinion hinein this field that Aß may be produced from its precursor hinein a physiologically häufig pathway and not necessarily hinein a pathological process. Indeed he found by using very simple tissue culture systems that Aß is produced and liberated under physiological conditions. This pivotal finding was a major breakthrough for the entire field, since it allowed elucidating the molecular principles behind Aß generation as well as the identification of the enzymes (the so-called secretases) involved rein generation and liberation of the peptide and finally the development of selective inhibitors to therapeutically lower Aß production in patients.
We are using interdisciplinary approaches ranging from biophysics, biochemistry and cellular and molecular biology to in vivo models and life imaging.
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Christian Haass, Professor of Metabolic Biochemistry at LMU Munich and spokesperson for the DZNE Munich, is known for his groundbreaking research hinein Alzheimer's disease. His work focuses on the molecular and cellular mechanisms of this disease rein order to gain fundamental insights into its development.
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Together with an interdiziplinary Mannschaft he uncovered the molecular mechanisms of Alzheimer's disease and identified target molecules for therapeutic treatment.
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You are allowed to have 10 minus points. You have failed the test if you get 11 or more minus points. If you incorrectly answer two questions each with five negativ points, you have also failed the test in spite of not exceeding the maximum number of negativ points; hinein Class B, questions with 5 points have a greater relevance in the theoretical test.
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The law prescribes attendance of 12 Beginners all purpose symbolic instruction code themes and two additional themes (irrelevant which); but you are recommended to have heard all the themes.
Leichte zweirädrige Kraftfahrzeuge mit einer durch die Bauart bestimmten Höchstgeschwindigkeit von nicht mehr denn 45 sachen, einer Nenndauerleistung/Nutzleistung von nicht eine größere anzahl als 4 kW und einem Verbrennungsmotor mit einem Hubraum von nicht etliche denn 50 cm³ oder Mehr Info einer anderen Antriebsform.
We work on the molecular and cellular mechanisms of neurodegeneration with a strong focus on Alzheimer’s disease and related disorders. We are searching for therapeutic targets within the amyloid cascade. Secretases, amyloid metabolism and microglial function are within the focus of our research.